Axoguard Nerve Protector^®

Axoguard Nerve Protector is the only small intestine submucosa (SIS) implant designed to protect injured and compressed nerves up to 40 mm.

Barrier to soft tissue attachments¹

protector innovations

Provides a protective barrier to separate the nerve from the surrounding tissues.¹
Minimizes the potential for soft tissue attachments to allow the nerve to glide.¹
Vascularizes and remodels into the patient’s own tissue.¹
Available in a variety of lengths and diameters for intra-operative versatility.

learn more

to order, obtain more information or report adverse events
contact axogen customer care:
Phone
888.axogen1 (888.296.4361)
Email
customercare@axogenInc.com
see sizing info below

the importance of biomaterials

In a pre-clinical study conducted to evaluate host tissue response, porcine small intestine submucosa (SIS, Axoguard Nerve Connector) performed significantly better than cross-linked bovine collagen type I (CLC, Integra NeuraGen^®) in all outcomes and categories.

Specifically, the study provided evidence that SIS had increased levels of M2 (pro-healing) macrophages which are indicative of a remodeling response, while CLC had increased levels of M1 (pro-inflammatory) macrophages indicative of a chronic inflammatory response.^2,3

M1 and M2 Macrophage Distribution

Host Response

#1

U.S. market leader*

in off-the-shelf nerve reconstruction solutions.

*IQVIA U.S. market data

6 mos

to remodel into protective layer.¹

remodels and vascularizes

to minimize potential for soft tissue attachments.

indications for use

INDICATIONS FOR USE: Axoguard Nerve Protector is indicated for the repair of peripheral nerve injuries where there is no gap. The device is supplied sterile and is intended for one-time use.

CONTRAINDICATIONS: This device is derived from porcine source and should not be used for patients with known sensitivity to porcine material.